Bergenin, Suatu Dihidroisokumarin dari Kayu dan Kulit Batang Shorea Stenoptera Burck§

Euis Holisotan Hakim, Rudiyansyah Rudiyansyah, Iqbal Musthapa, Koichi Takeya


Bergenin, a dihydroisocoumarin derivative of glucopyranosyl gallic acid had been isolated for the first time from ethyl acetate extracts of the heartwood and tree bark, together with (-)-α-viniferin from the tree bark of Shorea stenoptera. The structure of bergenin was elucidated based on analysis of spectroscopic data UV, IR, MS, 1H and 13C NMR. Bergenin showed weak cytotoxic activity against murine leukemia P-388 cells (IC50 >100 μg/mL), and also weak toxicity against Artemia salina shrimps (LC50 >500 μg/mL).

Full Text:




  • There are currently no refbacks.

View my Stats

Creative Commons License
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.


Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM), Center for Research and Community Services (CRCS) Building, 6th & 7th Floor, Institut Teknologi Bandung, Jalan Ganesha 10, Bandung 40132, Indonesia, Tel. +62-22-86010080, Fax.: +62-22-86010051; E-mail: