Flavonoid Compounds from the Herb of Krokot (Lygodium microphyllum) and their antioxidant activity against DPPH

Hadi Kuncoro, Kindi Farabi, Laode Rijai, Euis Julaeha, Unang Supratman, Yoshihito Shiono

Abstract


Six flavonoid compounds, kaempferol (1), quercetin (2), acacetin (3), quercetin-3-O-β-D-glucopyranoside (4), kaempferol-3-O-β-D-glucopyranoside (5), and isorhamnetin-3-O-β-D-glucopyranoside (6), were isolated from the methanol extract of the Lygodium microphyllum herb. The chemical structures of compounds 1-6 were identified on the basis of spectroscopic evidence and comparison with previously reported spectral data. Compounds 1-6 were isolated for first time from this plant. Their antioxidant activity against DPPH (2,2-Diphenyl-1-picrylhydrazyl) was evaluated. Among the compounds, quercetin (2) showed high antioxidant activity with IC50 values of 6.94 ± 0.03 μg/mL.


Keywords


Antioxidant; DPPH; flavonoids; Lygodium microphyllum; Lygodiaceae

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DOI: http://dx.doi.org/10.5614%2Fj.math.fund.sci.2018.50.2.7

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