https://journals.itb.ac.id/index.php/jmfs <p><img class="imgdesc" src="https://lppm.itb.ac.id/wp-content/uploads/sites/55/2021/08/JMFS_ITB_small.jpg" alt="" width="173" height="220" /></p> <p style="text-align: justify;"><em>Journal of Mathematical and Fundamental Sciences </em>welcomes full research articles in the area of Mathematics and Natural Sciences from the following subject areas: Astronomy, Chemistry, Earth Sciences (Geodesy, Geology, Geophysics, Oceanography, Meteorology), Life Sciences (Agriculture, Biochemistry, Biology, Health, Medical, Pharmacy), Mathematics, Physics, and Statistics. New submissions of mathematics articles starting in January 2020 are required to focus on applied mathematics with real relevance to the field of natural sciences.</p> <p style="text-align: justify;">Starting from Vol. 1, No. 1, 1961, full articles published are available online at ITB Journals and indexed by <a href="https://www.scopus.com/source/sourceInfo.uri?sourceId=21100268424&amp;origin=recordpage">Scopus</a>, <a href="https://mjl.clarivate.com/cgi-bin/jrnlst/jlresults.cgi?PC=MASTER&amp;ISSN=2337-5760">Web of Science (Emerging Sources Citation Index) - Clarivate Analytics</a>, <a href="https://www.scimagojr.com/journalsearch.php?q=21100268424&amp;tip=sid&amp;clean=0">Scimago JR</a>, <a href="https://doaj.org/toc/2338-5510">Directory of Open Access Journals (DOAJ)</a>, <a href="https://scholar.google.co.id/citations?hl=en&amp;user=xdqQsgUAAAAJ&amp;view_op=list_works&amp;sortby=pubdate">Google Scholar</a>, <a href="https://journals.indexcopernicus.com/Journal+of+Mathematical+and+Fundamental+Sciences,p24780956,3.html">Index Copernicus</a>, <a href="https://rzblx1.uni-regensburg.de/ezeit/searchres.phtml?bibid=AAAAA&amp;colors=7&amp;lang=en&amp;jq_type1=QS&amp;jq_term1=journal+of+mathematical+and+fundamental+sciences">The Elektronische Zeitschriftenbibliothek (EZB) by University Library of Regensburg</a>, <a href="https://atoz.ebsco.com/Titles/SearchResults/8623?SearchType=Contains&amp;Find=Journal+of+Mathematical+fundamental+Sciences&amp;GetResourcesBy=QuickSearch&amp;resourceTypeName=allTitles&amp;resourceType=&amp;radioButtonChanged=">EBSCO Open Science Directory</a>, <a href="https://asean-cites.org/aci_search/journal.html?b3BlbkpvdXJuYWwmaWQ9MTAzNzg">ASEAN Citation Index</a>, <a href="https://garuda.kemdikbud.go.id/journal/view/7389">Garba Rujukan Digital (Garuda)</a> and <a href="https://sinta.ristekbrin.go.id/journals/detail?id=667">Science and Technology Index (SINTA)</a>.</p> <p style="text-align: justify;">The journal has been also accredited for five years based on The Decree of Directorate General of Research and Development Strengthening, Ministry of Research, Technology and Higher Education of the Republic of Indonesia <a href="https://lppm.itb.ac.id/wp-content/uploads/sites/55/2021/12/Salinan-SK-Hasil-Akresitasi-Jurnal-Ilmiah-Periode-II-Tahun-2018.pdf">No. 030/E/KPT/2018</a>, dated on October 24th, 2018.</p> <p style="text-align: justify;">Published by Directorate for Research and Community Services, Institut Teknologi Bandung, in collaboration with <a href="https://www.lppm.itb.ac.id/wp-content/uploads/sites/55/2018/01/MoU-HAKI-JMFS-2018-BW.pdf">Indonesian Chemical Society (Himpunan Kimia Indonesia - HKI)</a>.</p> <p>ISSN: <a href="https://issn.brin.go.id/terbit/detail/1356660275">2337-5760</a>; E-ISSN: <a href="https://issn.brin.go.id/terbit/detail/1372762782" target="_blank" rel="noopener">2338-5510</a></p> <p><strong><u>Publication History</u></strong></p> <p><strong>Formerly known as:</strong></p> <ul> <li>ITB Journal of Science (2008 - 2012)</li> <li>Proceedings ITB Science and Technology (2003 - 2007)</li> <li>Proceedings ITB (1961 - 2002)</li> </ul> <p>Back issues also can be read online at <a href="https://journal.itb.ac.id">https://journal.itb.ac.id</a></p> Directorate for Research and Community Services (LPPM) ITB en-US Journal of Mathematical and Fundamental Sciences 2337-5760 https://journals.itb.ac.id/index.php/jmfs/article/view/25617 <p>Three triterpenoid compounds, belonging to the penta- and tetracyclic groups, were successively isolated from the stembark of <em>Aglaia cucullata</em> and identified as b-amyron (<strong>1</strong>), dammaradienon (<strong>2</strong>), and cabralealactone (<strong>3</strong>). After extensive extraction, chromatographic separation and purification, compounds <strong>1</strong> to <strong>3</strong> were gained. Spectroscopic analysis in addition to HRMS, FTIR, 1D and 2D NMR analysis were utilized to determine the chemical structure. After that, compounds <strong>1 </strong>to <strong>3</strong> were tested against breast cancer, melanoma as well as normal kidney cells (MCF-7, B16-F10, and CV-1, respectively). The resulted cytotoxicity test revealed that compound <strong>1</strong> had the best cytotoxicity against all cells compared with the other isolated compounds. This result suggests that the pentacyclic triterpenoid core in compound <strong>1</strong> increases cytotoxicity compared with a tetracyclic skeleton.</p> Kindi Farabi Wahyu Safriansyah Desi Harneti Hadi Kuncoro Sofa Fajriah Unang Supratman Copyright (c) 2025 Journal of Mathematical and Fundamental Sciences https://creativecommons.org/licenses/by-nc-nd/4.0 2025-11-29 2025-11-29 57 2 86 95 10.5614/j.math.fund.sci.2025.57.2.1