Flavonoid Compounds from the Herb of Krokot (Lygodium microphyllum) and their antioxidant activity against DPPH

Authors

  • Hadi Kuncoro Faculty of Pharmacy, Mulawarwan University, Samarinda, 75119, Kalimantan Timur
  • Kindi Farabi Faculty of Pharmacy, Mulawarwan University, Samarinda, 75119, Kalimantan Timur
  • Laode Rijai Faculty of Pharmacy, Mulawarwan University, Samarinda, 75119, Kalimantan Timur
  • Euis Julaeha Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Sumedang
  • Unang Supratman Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Sumedang
  • Yoshihito Shiono Department of Bioresources Engineering, Faculty of Agriculture, Yamagata University, Tsuruoka-shi, Yamagata 997-8555

DOI:

https://doi.org/10.5614/j.math.fund.sci.2018.50.2.7

Keywords:

Antioxidant, DPPH, flavonoids, Lygodium microphyllum, Lygodiaceae

Abstract

Six flavonoid compounds, kaempferol (1), quercetin (2), acacetin (3), quercetin-3-O-β-D-glucopyranoside (4), kaempferol-3-O-β-D-glucopyranoside (5), and isorhamnetin-3-O-β-D-glucopyranoside (6), were isolated from the methanol extract of the Lygodium microphyllum herb. The chemical structures of compounds 1-6 were identified on the basis of spectroscopic evidence and comparison with previously reported spectral data. Compounds 1-6 were isolated for first time from this plant. Their antioxidant activity against DPPH (2,2-Diphenyl-1-picrylhydrazyl) was evaluated. Among the compounds, quercetin (2) showed high antioxidant activity with IC50 values of 6.94 0.03 μg/mL.

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Published

2018-08-31

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