Flavonoids from Macaranga lowii
DOI:
https://doi.org/10.5614/itbj.sci.2012.44.1.2Abstract
A new isoprenylated dihydroflavonolderivative, macalowiinin (1), together with two known flavonoids 4'-O-methyl-8-isoprenylnaringenin(2) and 4'-O-methyl-5,7,4'-trihydroxyflavone (3) (= acasetin), have been isolated from the methanol extract of the leaves of Macaranga lowii. The structures of these compounds were determined based on UV, NMR, and mass spectral data, and optical rotation. Preliminary cytotoxic evaluation of compounds 1 "? 3 against P-388 cellsshowed that compound 3 is the most active with IC50 was 58.7 mM.References
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